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Antigenic Specificity | Synaptophysin |
Clone | SYP02 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synaptophysin Monoclonal Antibody (SYP02). Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96. |
Immunogen | n/a |
Other Names | major synaptic vesicle protein P38 |
Gene, Accession # | Entrez: 20977, 24804, 6855; Uniprot: P07825, P08247, Q62277 |
Catalog # | MA5-11575 |
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Order / More Info | Synaptophysin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 14648843, 15719276, 19590421, 19913282, 20173504, 22867429, 22868530 |
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