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Antigenic Specificity | Synaptophysin |
Clone | SP11 |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synaptophysin Monoclonal Antibody (SP11). Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96. |
Immunogen | n/a |
Other Names | major synaptic vesicle protein P38 |
Gene, Accession # | Entrez: 20977, 24804, 6855; Uniprot: P07825, P08247, Q62277 |
Catalog # | MA5-14532 |
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Order / More Info | Synaptophysin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16491376, 16614351, 17599745, 17616990, 18177458, 18304754, 18373697, 18423895, 18480005, 18498427, 18844937, 19605911, 19788621, 20216406, 20719821, 21216781, 21403398, 21765392, 21893434, 22422124, 22741527, 23080156, 23109924, 23358695, 24218309, 24228104, 24468036, 24898918, 25142799, 26643927, 26785948, 27056040, 27620277, 27965908 |
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