| 产品详情 |
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| Antigenic Specificity | AKT1 (pT308) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-AKT1 (Thr308) Antibody detects endogenous levels of AKT1 only when phosphorylated at Threonine 308. an AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus. Tumorigenic in a mouse lymphoma model and activated (by phospho-Akt staining) and/or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Inhibitor: RX-0201. Substrates include tuberin, Bad, Forkhead transcription factors, caspase-9, and glycogen synthase kinase-3. |
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| Immunogen | n/a |
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| Other Names | AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha; RAC-alpha serine/threonine kinase; kinase Akt1; CWS6; PRKBA; RAC-ALPHA; AKT1; RAC-alpha serine/threonine-protein kinase; Protein kinase B alpha; Proto-oncogene c-Akt; PKB alpha; PK; RAC-PK-beta; Protein kinase; Akt-2; beta RAC-PK-gamma; Protein kinase Akt-3; gamma PKB; gamma STK-2 |
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| Gene, Accession # | AKT1, Gene ID: 207, SwissProt: P31749 |
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| Catalog # | abx010398 |
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| Price | |
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| Order / More Info | AKT1 (pT308) Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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