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产品名称 JNK1/JNK2/JNK3 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-38289
产品价格 现货询价，电话：010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityJNK1/JNK2/JNK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsImmunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Western Blot: 1:500-1:1000
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DescriptionJNK1/JNK2/JNK3 Polyclonal Antibody. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38. JNK3 (MK10, MAPK10, PRKM10) is activated by pro-inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c-Jun and ATF2. This is important for AP-1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress-in
Immunogenn/a
Other NamesJNK 46, JNK 55, JNK, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2ALPHA, JNK2B, JNK2BETA, JNK3, JNK3A, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 8, MAPK 9, MAPK10, MAPK8, MAPK9, MGC50974, Mitogen activated protein kinase 10, Mitogen activated protein kinase 8, Mitogen activated protein kinase 9, JNK3; JNK3A; PRKM10; p54bSAPK; MAPK10
Gene, Accession #Entrez: 116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602; Uniprot: P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Catalog #PA5-38289
Price
Order / More InfoJNK1/JNK2/JNK3 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料