产品详情 |
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Antigenic Specificity | NUDT15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:1000-1:2500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NUDT15 Polyclonal Antibody. Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA. |
Immunogen | n/a |
Other Names | MTH2, RP11-90M2.1, 8-oxo-dGTPase NUDT15, A730068G11Rik, mutT homolog 2, nucleoside diphosphate-linked moiety X motif 15, nudix motif 15, nudix-type motif 15, probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 |
Gene, Accession # | Entrez: 55270; Uniprot: Q9NV35 |
Catalog # | PA5-58614 |
Price | |
Order / More Info | NUDT15 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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