产品详情 |
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Antigenic Specificity | LOX-1 |
Clone | 15C4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human LOX-1. Lectin-like oxidized LDL receptor 1 (LOX-1), also known as CLEC8A, is a 31 kD, single pass, type II, transmembrane protein, member of the C-type lectin superfamily. LOX-1 is a scavenger receptor involved in endocytosis, phagocytosis, and cytokine production. LOX-1 is expressed by endothelial cells, smooth muscle cells, platelets, fibroblasts, and macrophages, and is upregulated by inflammatory and oxidative stimuli. LOX-1 recognized numerous ligands including lipoproteins, apoptotic cells heat shock proteins, C-reactive protein, and oxidized LDL. LOX-1 is implicated in atherosclerosis and vascular inflammation. |
Immunogen | LOX-1 ectodomain:Fc fusion protein |
Other Names | OLR1, LOX1, LOXIN, SLOX1, CLEC8A, SCARE1 |
Gene, Accession # | Gene ID: 4973 |
Catalog # | 358603 |
Price | |
Order / More Info | LOX-1 Antibody from BIOLEGEND |
Product Specific References | n/a |
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