| 产品详情 |
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| Antigenic Specificity | LOX-1 |
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| Clone | 15C4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-human LOX-1. Lectin-like oxidized LDL receptor 1 (LOX-1) also known as CLEC8A is a 31 kD single pass type II transmembrane protein and member of the C-type lectin superfamily. LOX-1 is a scavenger receptor and is involved in endocytosis, phagocytosis, and cytokine production. CLEC8A is expressed by endothelial cells, smooth muscle cells, platelets, fibroblasts, macrophages, and is upregulated by inflammatory and oxidative stimuli. LOX-1 recognizes numerous ligands including lipoproteins, apoptotic cells heat shock proteins, C-reactive protein, and oxidized LDL. LOX-1 is implicated in atherosclerosis and vascular inflammation. |
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| Immunogen | LOX-1 ectodomain: Fc fusion protein |
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| Other Names | OLR1, LOX1, LOXIN, SLOX1, CLEC8A, SCARE1 |
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| Gene, Accession # | Gene ID: 4973 |
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| Catalog # | 358606 |
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| Price | |
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| Order / More Info | LOX-1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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