| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | AktS1/PRAS40 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:1,000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | AktS1/PRAS40 Polyclonal Antibody. The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells. |
|---|
| Immunogen | n/a |
|---|
| Other Names | 40 kDa proline-rich AKT substrate; OTTHUMP00000196756; OTTHUMP00000196760; proline-rich AKT1 substrate 1; proline-rich Akt substrate, 40 kDa |
|---|
| Gene, Accession # | Entrez: 84335; Uniprot: Q96B36 |
|---|
| Catalog # | A301-201A-M |
|---|
| Price | |
|---|
| Order / More Info | AktS1/PRAS40 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|