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| Antigenic Specificity | AktS1/PRAS40 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AktS1/PRAS40 Polyclonal Antibody. The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells. |
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| Immunogen | n/a |
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| Other Names | 40 kDa proline-rich AKT substrate; OTTHUMP00000196756; OTTHUMP00000196760; proline-rich AKT1 substrate 1; proline-rich Akt substrate, 40 kDa |
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| Gene, Accession # | Entrez: 84335; Uniprot: Q96B36 |
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| Catalog # | A301-202A-T |
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| Price | |
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| Order / More Info | AktS1/PRAS40 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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