| 产品详情 |
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| Antigenic Specificity | Human CD244 |
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| Clone | 2-69 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-human CD244 (2B4). CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8 T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression. |
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| Immunogen | Human NK cells |
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| Other Names | 2B4, NAIL, SLAMF4 |
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| Gene, Accession # | Gene ID: 51744 |
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| Catalog # | 393511 |
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| Price | |
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| Order / More Info | Human CD244 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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