| 产品详情 |
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| Antigenic Specificity | Human CD16 |
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| Clone | 3G8 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, capuchin monkey, chimpanzee, cynomolgus, marmoset, pigtailed macaque, rhesus, sooty mangabey, squirrel monkey |
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| Isotype | IgG1, κ |
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| Format | purified, low endotoxin, azide-free |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), CyTOF®, Block, IHC, IP, Stim |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ultra-LEAF™ Purified anti-human CD16. CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). |
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| Immunogen | Human PMN cells |
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| Other Names | FcγRIII |
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| Gene, Accession # | Gene ID: 2214 |
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| Catalog # | 302049 |
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| Price | |
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| Order / More Info | Human CD16 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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