| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Human CD16 |
|---|
| Clone | 3G8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, capuchin monkey, chimpanzee, cynomolgus, marmoset, pigtailed macaque, rhesus, sooty mangabey, squirrel monkey |
|---|
| Isotype | IgG1, κ |
|---|
| Format | TotalSeq™-C oligomer conjugate |
|---|
| Size | 10 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | TotalSeq™-C0083 anti-human CD16. CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). |
|---|
| Immunogen | Human PMN cells |
|---|
| Other Names | FcγRIII |
|---|
| Gene, Accession # | Gene ID: 2214 |
|---|
| Catalog # | 302065 |
|---|
| Price | |
|---|
| Order / More Info | Human CD16 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|