| 产品详情 |
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| Antigenic Specificity | IL-34 |
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| Clone | C054-35 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | purified, azide-free |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | ELISA Capture |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-mouse IL-34. IL-34 is a homodimeric glycoprotein which contains 241 amino acids. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage differentiation, proliferation, and survival. Elevated levels of IL-34 are seen in the plasma of rheumatoid arthritis patients, but can be decreased in response to therapy. IL-34 levels are also increased in the serum of cancer patients and are associated with poor prognosis. Mouse IL-34 shares 71% sequence identity with human IL-34 on the amino acid level. |
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| Immunogen | Recombinant mouse IL-34 |
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| Other Names | IL34, Interleukin 34, C16orf77 |
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| Gene, Accession # | Gene ID: 76527 |
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| Catalog # | 147202 |
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| Price | |
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| Order / More Info | IL-34 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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