| 产品详情 |
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| Antigenic Specificity | IL-32 |
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| Clone | KU32-07 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA Capture |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human IL-32α. Interleukin 32 (IL-32), previously known as a transcript (NK4), is produced by mitogen-activated lymphocytes, by IFNγ-activated epithelial cells or by IL-12 and IL-18-activated NK cells. Its expression is increased following activation of T-cells by mitogens or the activation of NK cells by IL-2. IL-32 activates NF-κB and p38 MAPK cytokine signal pathways. It has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues. IL-32 exists in at least four differentially spliced isoforms (α, β, γ and δ) with predicted molecular weight: ~26 kD. IL-32α is the shortest and most abundant of four potential splice variants of the pro-inflammatory cytokine IL-32. Potential modifications include myristoylation and N-glycosylation. Transfected IL-32α was more likely to be cell-associated as compared to IL-32β, suggesting an intracellular function. |
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| Immunogen | Recombinant human IL-32α |
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| Other Names | IL-32alpha, Interleukin 32 alpha, Natural Killer Transcript 4 (NK4), TNF-α-inducible factor (TAIF) |
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| Gene, Accession # | Gene ID: 9235 |
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| Catalog # | 513301 |
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| Price | |
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| Order / More Info | IL-32 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 18997060,19762563,22890997 |
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