| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | IL-31 |
|---|
| Clone | 1C2B07 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-mouse IL-31. IL-31, mainly produced by activated CD4+ T cells, is a helical cytokine belonging to the gp130/IL-6 cytokine family. IL-31 is closely related in structure to IL-6, IL-11, and IL-27. Binding of IL-31 to its receptor activates JAK/STAT, PI3K/AKT, and MAPK pathways. IL-31 acts on a broad range of immune and non-immune cells and thus possesses potential pleiotropic physiological functions, such as regulating hematopoiesis and immune response. Transgenic mice overexpressing IL-31 developed severe dermatitis, indicating that IL-31 is involved in skin immunity. |
|---|
| Immunogen | Full length mouse IL-31 recombinant protein expressed in E. coli. |
|---|
| Other Names | Interleukin-31 (IL31) |
|---|
| Gene, Accession # | Gene ID: 76399 |
|---|
| Catalog # | 660602 |
|---|
| Price | |
|---|
| Order / More Info | IL-31 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|