产品详情 |
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Antigenic Specificity | IL-27 |
Clone | B0315A10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-IL-27 p28. IL-27 is a heterodimeric cytokine that is composed of two subunits (p28 and EBI3). It plays a critical role in T-cell proliferation and differentiation. It also drives rapid clonal expansion of naive but not memory CD4 T cells. IL-27 is a potent inhibitor of Th17 cell development and IL-17 production. IL-27 subunit p28 alone is able to inhibit the production of IL-17 by CD4 and CD8 T cells. Furthermore, IL-27 plays an important role in antitumor and antiangiogenic activity through the increase in the production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9. |
Immunogen | Recombinant human IL-27. |
Other Names | Interleukin-27 Subunit Alpha, IL-27 (28K subunit) |
Gene, Accession # | Gene ID: 246778 |
Catalog # | 676902 |
Price | |
Order / More Info | IL-27 Antibody from BIOLEGEND |
Product Specific References | n/a |
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