产品详情 |
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Antigenic Specificity | VEGF |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA Detection |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biotin anti-human VEGF. VEGF (also known as VEGF-A) is a signaling protein with strong vascular permeability activity that stimulates the formation of new blood vessels during the processes of vasculogenesis and angiogenesis. It is a member of the vascular endothelial growth factor family, which in mammals is comprised of VEGF-A, VEGF-B, VEGF-C, VEGF-D, and PlGF (placental growth factor). There are multiple isoforms of VEGF that result from alternative splicing of mRNA. VEGF binds and activates two tyrosine kinase receptors, VEGFR1 (Flt-1) and VEGFR2 (KDR/Flk-1), through which VEGF exerts its mitogenic effects. VEGF is highly expressed in solid tumors of breast, lung, renal, colorectal, and hepatic origin. Additionally, it significantly contributes to ascites tumor formation. Beyond cancer, VEGF has also been associated with multiple pathogenic conditions including rheumatoid arthritis, age-related macular degeneration, Crow-Fukase syndrome, sclerosis and Alzheimer's disease. |
Immunogen | Recombinant protein |
Other Names | VEGFA, VEGF-A, VPF, MVCD1, vascular endothelial growth factor |
Gene, Accession # | n/a |
Catalog # | 522503 |
Price | |
Order / More Info | VEGF Antibody from BIOLEGEND |
Product Specific References | n/a |
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