| 产品详情 |
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| Antigenic Specificity | NMDAR1 |
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| Clone | N308/48 |
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| Host Species | Mouse |
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| Reactive Species | rat, mouse |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HRP anti-NMDAR1. Glutamate activated Ion channels that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDA receptor plays an essential role in the induction of LTP in the CA1 and dentate areas of the hippocampus as the specific NMDA antagonist, APV blocks LTP in these areas. This receptor has also been linked to neuronal development and it has been implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. |
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| Immunogen | This monoclonal antibody was raised against a fusion protein corresponding to amino acids 42-361 (extracellular, N-terminus) of rat GluN1/NR1 glutamate receptor protein. |
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| Other Names | GluN1/NR1 glutamate receptor, Glutamate receptor ionotropic, NMDA 1, NMD-R1, neurotransmitter receptor, NMDA R1 receptor C1 cassette, N-methyl-D-aspartate glutamate receptor, glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, MMS-5145-100 |
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| Gene, Accession # | Gene ID: 24408 |
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| Catalog # | 818604 |
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| Price | |
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| Order / More Info | NMDAR1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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