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| Product Name | Cholesterol Uptake Cell-Based Assay Kit |
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| Description | Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. The mechanisms controlling cholesterol absorption are important to understand for the prevention and treatment of hypercholesterolemia. Cayman's Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently-tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control. |
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| Size | 1 ea |
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| Concentration | n/a |
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| Applications | Flow Cytometry |
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| Other Names | assays kits measures measurements cells hormones intermediates bile acids biosynthesis body cholesterols homeostasis de novo dietary absorption biliary clearance excretion plasma hypercholesterolemia cardiovascular diseases serum hepatic Ezetimibe inhibitors inhibits inhibition intestinal uptake enterocytes proteins Niemann-Pick C1 Like 1 NPC1L1 genes influx efflux intraluminal molecules membranes modulators NBD cultured U18666A inhibitor inhibits inhibition positive controls U 18666A U-18666A |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 600440-1EA |
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| Order / More Info | Cholesterol Uptake Cell-Based Assay Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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