产品详情 |
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Antigenic Specificity | FOX3 |
Clone | 1B7 |
Host Species | Mouse |
Reactive Species | human, cow, porcine, mouse, rat, and other mammals |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | IHC-P, Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-FOX3 (NeuN). Fox3 is one of a family of 3 mammalian Fox homologues. Fox was discovered in C. elegans as a gene involved in sex determination, and the name Fox is an acronym of Feminizing locus on X. The Fox protein and its 3 mammalian homologues are all about 46 kD proteins, each of which includes a central highly conserved RRM type RNA recognition motif, which corresponds to a small ~70 amino acid structure consisting of 4 beta strands and two alpha-helices. Fox3 is a protein which has a function in RNA splicing and is expressed heavily and specifically in neuronal nuclei. The 1B7 antibody reveals strong nuclear and distal cytoplasmic staining for Fox3/NeuN and the complete absence of staining of astrocytes and other kinds of non-neuronal cells. This Fox3/NeuN antibody is therefore an excellent marker of neuronal cells. |
Immunogen | Antibody was raised against the N-terminal 100 amino acids of human Fox3 as expressed in and purified from E. coli. |
Other Names | RNA binding protein fox-1 homolog 3, fox-1 homolog C, neuronal nuclei, hexaribonucleotide binding protein 3, SIG-39860-100 |
Gene, Accession # | Gene ID: 146713 |
Catalog # | 834501 |
Price | |
Order / More Info | FOX3 Antibody from BIOLEGEND |
Product Specific References | n/a |
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