| 产品详情 |
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| Antigenic Specificity | CD344 (Frizzled-4) |
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| Clone | CH3A4A7 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, cynomolgus |
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| Isotype | IgG1, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-human CD344 (Frizzled-4). CD344 is a member of the Frizzled family, known as Frizzled-4 (Fz4, FZD4, hFz4, or FzE4). Ten frizzled member have been identified in humans. Human FZD4 gene has been mapped to chromosome 11q14-q21. FZD4 is a 48-53 kD seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins and norrie. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD4 is a neuronal stem cell marker and is also expressed on fetal neuronal progenitor cells and neuronal intestinal cells. Kidney, lung, brain and liver express abundant of FZD4. It has been reported that FZD4 controls retinal and inner ear angiogenesis, participates in the regulation of embryonic development, tissue and cell polarization and proliferation. |
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| Immunogen | WERI-RB-1 retinoblastoma cells |
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| Other Names | Frizzled-4 receptor, Frizzled-4, Fz4, FZD4, FzE4, hFz4, FEVR, EVR1 |
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| Gene, Accession # | Gene ID: 8322 |
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| Catalog # | 326606 |
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| Price | |
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| Order / More Info | CD344 (Frizzled-4) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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