| 产品详情 |
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| Antigenic Specificity | CD266 (Fn14, TWEAK Receptor) |
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| Clone | ITEM-1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD266 (Fn14, TWEAK Receptor). TWEAK receptor is also known as fibroblast growth factor inducible 14 kD protein (Fn14) or CD266. It is a 14 kD transmembrane protein that is expressed on a variety of tissue types. This receptor binds TWEAK and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The TWEAK receptor is rapidly induced during liver regeneration and m play a role in hepatocyte growth. TWEAK receptor engagement can induce cell death and may play a role in inflammation. The ITEM-1 antibody is useful for flow cytometric analysis, induction of tumor cells apoptosis or necrotic cell death, enhancing endothelial cell proliferation, and immunohistochemistry on frozen tissues. |
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| Immunogen | Human Fn14 transfected P815 |
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| Other Names | Fn14, TWEAK Receptor, TNFRSF12A |
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| Gene, Accession # | Gene ID: 51330 |
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| Catalog # | 314002 |
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| Price | |
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| Order / More Info | CD266 (Fn14, TWEAK Receptor) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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