| 产品详情 |
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| Antigenic Specificity | CD266 (Fn14, TWEAK Receptor) |
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| Clone | ITEM-4 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), IHC, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human/mouse CD266 (Fn14, TWEAK R). CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. |
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| Immunogen | Human Fn14 transfected P815 |
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| Other Names | Fn14, TWEAK Receptor, TNFRSF12A |
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| Gene, Accession # | Gene ID: 27279, 51330 |
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| Catalog # | 314102 |
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| Price | |
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| Order / More Info | CD266 (Fn14, TWEAK Receptor) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 24416188,25524063 |
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