产品详情 |
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Antigenic Specificity | IL-16 |
Clone | 14.1 |
Host Species | Mouse |
Reactive Species | human, cross-reactivity: mouse |
Isotype | IgG2a |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human IL-16. Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16. |
Immunogen | Peptide corresponding to amino acids 615 to 630 (RRKSLQSKETTAAGDS) of IL-16 |
Other Names | Interleukin-16 |
Gene, Accession # | Gene ID: 3603 |
Catalog # | 519106 |
Price | |
Order / More Info | IL-16 Antibody from BIOLEGEND |
Product Specific References | n/a |
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