| 产品详情 |
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| Antigenic Specificity | CD85k |
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| Clone | H1.1 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-mouse CD85k (gp49 Receptor). gp49, also known as ILT3, gp49b1 or CD85k, is a 49 kD glycoprotein expressed on activated NK cells and myeloid cells. It structurally resembles killer inhibitory receptors (KIR). gp49B is a type I membrane protein belonging to the Ig superfamily and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), while gp49A is a truncated molecule without ITIM. Upon activation following interaction with integrin avb3, the cytoplasmic tail associates with SHP-1 and SHP-2, which results in downregulation of cell activation and cytokine production. |
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| Immunogen | gp49B-Fc fusion protein |
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| Other Names | Leukocyte immunoglobulin-like receptor, subfamily B, member 4 (Lilrb4), gp49B, ILT3, gp49 |
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| Gene, Accession # | Gene ID: 14728 |
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| Catalog # | 144906 |
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| Price | |
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| Order / More Info | CD85k Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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