| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD127 (IL-7Ra) |
|---|
| Clone | A019D5 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
|---|
| Isotype | IgG1, κ |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-human CD127 (IL-7Rα). CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. |
|---|
| Immunogen | Recombinant human CD127 |
|---|
| Other Names | IL-7 receptor α chain, IL-7Rα |
|---|
| Gene, Accession # | Gene ID: 3575 |
|---|
| Catalog # | 351302 |
|---|
| Price | |
|---|
| Order / More Info | CD127 (IL-7Ra) Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|