| 产品详情 |
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| Antigenic Specificity | CD127 (IL-7Ra) |
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| Clone | A019D5 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG1, κ |
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| Format | Pacific Blue™ conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Pacific Blue™ anti-human CD127 (IL-7Rα). CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. |
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| Immunogen | Recombinant human CD127 |
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| Other Names | IL-7 receptor α chain, IL-7Rα |
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| Gene, Accession # | Gene ID: 3575 |
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| Catalog # | 351305 |
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| Price | |
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| Order / More Info | CD127 (IL-7Ra) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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