| 产品详情 |
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| Antigenic Specificity | Caspase-1 |
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| Clone | 5B10 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Caspase-1. Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd. |
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| Immunogen | Bacterial fusion protein (p20) |
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| Other Names | ICE |
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| Gene, Accession # | Gene ID: 834 |
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| Catalog # | 645101 |
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| Price | |
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| Order / More Info | Caspase-1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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