产品详情 |
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Antigenic Specificity | CaMKII |
Clone | 6G9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-F |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-CaMKII. The Ca2+/calmodulin (CaM)-dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. CaMKII is expressed as a multimeric protein, which typically is comprised of 12 subunits in physiological conditions. CaMKII is an important member of the calcium/calmodulin-activated protein kinase family. It phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors. CaMKII plays critical roles in neural synaptic stimulation and T cell receptor signaling. Recent studies suggested that high levels of CaMKII is also expressed in variety of cancers. It regulates proliferation, differentiation and survival of cancer cells. |
Immunogen | 50% pure type II CaM kinase, purified through Calmodulin-Sepharose step. |
Other Names | CAMK2, CaM kinase II, Calcium/calmodulin-dependent protein kinase type II subunit alpha |
Gene, Accession # | Gene ID: 815 |
Catalog # | 688602 |
Price | |
Order / More Info | CaMKII Antibody from BIOLEGEND |
Product Specific References | n/a |
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