| 产品详情 |
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| Antigenic Specificity | CD201 (EPCR) |
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| Clone | RCR-401 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | TotalSeq™-A oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-A0069 anti-human CD201 (EPCR). Endothelial protein C receptor (EPCR), also known as CD201, is a 46 kD N-glycosylated type I transmembrane protein primarily expressed on the endothelial cells of arteries and veins in heart and lung. It is also expressed at high levels on a subset of hematopoietic stem cells and a subset of dendritic cells. CD201 functions as a primary receptor for protein C activation, which results in inhibition of both intrinsic and extrinsic coagulation pathways. It also plays an important role in many pathophysiologic processes, such as inflammation responses to infection, trauma, hematopoiesis, and autoimmune response. Deletion of the CD201 gene in knock-out mice leads to embryonic lethality before embryonic day 10, indicating that CD201 expression is critical for embryo development. In humans, mutations of CD201 have been associated with venous thromboembolism and myocardial infarction as well as with late fetal loss during pregnancy. |
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| Immunogen | n/a |
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| Other Names | Endothelial protein C receptor, protein C receptor, PROCR, activated protein C receptor, APC receptor |
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| Gene, Accession # | Gene ID: 10544 |
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| Catalog # | 351907 |
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| Price | |
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| Order / More Info | CD201 (EPCR) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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