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| Antigenic Specificity | CD158e1 (KIR3DL1, NKB1) |
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| Clone | DX9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | PerCP-Cyanine5.5 conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PerCP/Cyanine5.5 anti-human CD158e1 (KIR3DL1, NKB1). CD158e1, also known as NKB1, is a 70 kD member of the immunoglobulin superfamily that is expressed on a subset of natural killer cells and T cells at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2-type domains. The interaction of NKB1 with specific HLA-B antigens on a target cell (the HLA-Bw4 allele, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease. |
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| Immunogen | Human NK cell clone VL186-1.6 |
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| Other Names | NKAT3, NKB1, KIR-NKB1, p70 |
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| Gene, Accession # | Gene ID: 3811 |
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| Catalog # | 312717 |
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| Order / More Info | CD158e1 (KIR3DL1, NKB1) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17641029,18025130,25672754 |
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