产品名称 CD226 (DNAM-1) Antibody from BIOLEGEND
产品货号 133630
产品价格 现货询价,电话:010-67529703
产品规格 500 µg
产品品牌 BIOLEGEND
产品概述
产品详情
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Antigenic SpecificityCD226 (DNAM-1)
CloneTX42.1
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a, κ
Formatpurified
Size500 µg
Concentrationn/a
ApplicationsFlow Cytometry (FC), IHC-F
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DescriptionPurified anti-mouse CD226 (DNAM-1). Mouse CD226 (DNAM-1) is a 65 kd glycoprotein of a member of Ig super-family adhesion molecule containing 2 immunoglobulin-like domains. It is associated with leukocyte function associated antigen-1 (LFA-1) involving in TCR-mediated signal transduction for T cell proliferation and differentiation. CD226 is also involved in NK cell and T cell mediated cytotoxicity against certain tumors. CD226 (DNAM-1) is constitutively expressed on naïve CD8+ and CD4+ T cells, macrophages, and NK cells. It was reported that CD226 expression is up-regulated on Th1 cells, but down-regulated on Th2 and Th0 cells. CD155 and CD112 are the ligands for CD226.
ImmunogenMouse DNAM-1 transfected cells
Other NamesDNAM-1, PTA1(platelet and T cell activation antigen 1), TLISA1, LFA-1 associated Molecule PTA-1
Gene, Accession #Gene ID: 225825
Catalog #133630
Price
Order / More InfoCD226 (DNAM-1) Antibody from BIOLEGEND
Product Specific Referencesn/a
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