产品详情 |
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Antigenic Specificity | CD226 (DNAM-1) |
Clone | TX42.1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC-F |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD226 (DNAM-1). Mouse CD226 (DNAM-1) is a 65 kd glycoprotein of a member of Ig super-family adhesion molecule containing 2 immunoglobulin-like domains. It is associated with leukocyte function associated antigen-1 (LFA-1) involving in TCR-mediated signal transduction for T cell proliferation and differentiation. CD226 is also involved in NK cell and T cell mediated cytotoxicity against certain tumors. CD226 (DNAM-1) is constitutively expressed on naïve CD8+ and CD4+ T cells, macrophages, and NK cells. It was reported that CD226 expression is up-regulated on Th1 cells, but down-regulated on Th2 and Th0 cells. CD155 and CD112 are the ligands for CD226. |
Immunogen | Mouse DNAM-1 transfected cells |
Other Names | DNAM-1, PTA1(platelet and T cell activation antigen 1), TLISA1, LFA-1 associated Molecule PTA-1 |
Gene, Accession # | Gene ID: 225825 |
Catalog # | 133630 |
Price | |
Order / More Info | CD226 (DNAM-1) Antibody from BIOLEGEND |
Product Specific References | n/a |
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