| 产品详情 |
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| Antigenic Specificity | Beclin-1 |
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| Clone | O93F3 |
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| Host Species | Mouse |
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| Reactive Species | human, rat, mouse |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HRP anti-Beclin-1. Beclin-1 plays a central role in autophagy and is involved in autophagosome formation. It acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Beclin-1 is necessary for the initiation of autophagy, and it has been shown to be reduced in the brains of patients with Alzheimer’s disease. Reduced Beclin-1 levels lead to decreased autophagy, the accumulation of Aβ peptides, and neurodegeneration in mouse models of Alzheimer's disease. |
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| Immunogen | Full length recombinant human Beclin-1 protein (NP_003757) produced in HEK293T cells |
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| Other Names | ATG6 Autophagy Related 6 Homolog, VSP30 |
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| Gene, Accession # | Gene ID: 8678 |
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| Catalog # | 849703 |
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| Price | |
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| Order / More Info | Beclin-1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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