| 产品详情 |
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| Antigenic Specificity | Bcl-XS/L |
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| Clone | 2H12 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat, porcine |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IP, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Bcl-XS/L. Bcl-X belongs to Bcl-2 family, and has several alternative splicing isoforms. It plays a critical role in control of apoptosis. The large isoform Bcl-XL (26kD) contains the highly conserved BH1/BH2 domain and protects cells from apoptosis, whereas the short isoform, Bcl-XS (19kD), which lacks of conserved BH1/BH2 domain, promotes apoptosis by interacting with Bcl-XL and Bcl-2. Bcl-XS is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-XL is found in long-lived, post-mitotic cells, such as adult brain. |
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| Immunogen | Bcl-XS/L (3-14 amino acid, conserved in both human and mouse) |
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| Other Names | Apoptosis regulator Bcl-X, Bcl-2-like 1 protein |
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| Gene, Accession # | Gene ID: 598 |
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| Catalog # | 633902 |
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| Price | |
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| Order / More Info | Bcl-XS/L Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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