| 产品详情 |
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| Antigenic Specificity | Bcl-6 |
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| Clone | 7D1 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-human/mouse Bcl-6. B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer, member of the BTB-POZ zinc finger family. It contains 1 BTB (POZ) domain and 6 C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor, master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switch and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells. |
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| Immunogen | Sequence 226-398 of murine BCL6 fused with GST |
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| Other Names | B-cell lymphoma 6 (Bcl6), BCL5, LAZ3, BCL6A, ZNF51, ZBTB27 |
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| Gene, Accession # | Gene ID: 604 |
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| Catalog # | 358512 |
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| Price | |
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| Order / More Info | Bcl-6 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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