| 产品详情 |
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| Antigenic Specificity | Apo E |
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| Clone | A17067B |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), Direct ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Apo E, 109-116. Apolipoprotein E (Apo E) belongs to a class of apolipoproteins that mediate the binding, internalization, and catabolism of lipoprotein particles. Apo E is produced by the liver and macrophages in peripheral tissues where it regulates cholesterol metabolism. In the central nervous system, Apo E is primarily produced by astrocytes and plays an important role in transporting cholesterol to neurons via Apo E receptors. Apo E has three alleles (ApoE2, ApoE3 and ApoE4) that differ from each other by only one or two amino acids at positions 112 and 158. ApoE 4 is one of the largest known genetic risk factors for late-onset Alzheimer's disease. Furthermore, Apo E is associated with cardiovascular disease, Lipoprotein Glomerulopathy and Sea-Blue Histiocyte Disease. |
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| Immunogen | KLH conjugated APOE peptide encompassing amino acids 109-116. |
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| Other Names | Apolipoprotein E, Alzheimer Disease 2, LDLCQ5, LPG, AD2 |
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| Gene, Accession # | Gene ID: 348 |
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| Catalog # | 852702 |
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| Price | |
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| Order / More Info | Apo E Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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