| 产品详情 |
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| Antigenic Specificity | Apo E |
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| Clone | E6D7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 1 ml |
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| Concentration | n/a |
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| Applications | ELISA, Western Blot (WB), IHC, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Apo E. Apo-E is a class of apolipoprotein primarily synthesized in the liver, but is also found in other tissues such as brain, kidneys, and spleen. Apo-E is a protein component of serum chylomicron and lipoprotein particles, playing essential roles in cholesterol transportation, homeostasis, and metabolism. The expression of Apo-E is induced by cholesterol-rich diets and hyperlipoproteinemia. In the central nervous system, Apo-E is produced by astrocytes and microglia. The Apo-E-containing lipoprotein particles play important functions in brain injury repair, neurogenesis, and synaptic plasticity. Apo-E has been found to be involved in the regulation of amyloid-β aggregation and clearance. Genetic polymorphisms of Apo-E are associated with neuron degenerative disorders including Alzheimer's disease. |
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| Immunogen | This antibody was raised against a synthetic peptide corresponding to amino acids surrounding the polymorphic amino acid position 158 of Apo-E. |
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| Other Names | Apolipoprotein E, apolipoprotein E3, AD2, LDLCQ5, LPG, ApoE, SIG-39750-1000 |
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| Gene, Accession # | Gene ID: 348 |
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| Catalog # | 803403 |
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| Price | |
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| Order / More Info | Apo E Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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