产品详情 |
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Antigenic Specificity | Betatrophin |
Clone | M0917B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Betatrophin (ANGPTL8). Betatrophin (ANGPTL8) is a hormone that plays important roles in triglyceride (TG) and glucose metabolism. It is primarily expressed in liver and fat cells. Transient expression of betatrophin in mouse liver cells significantly promotes pancreatic β cell proliferation, expands β cell mass, and improves glucose tolerance. Absence of betatrophin profoundly disrupts TG metabolism. These findings suggest that betatrophin could prove clinically important in the treatment of diabetes and other degenerative and metabolic disorders. |
Immunogen | Recombinant human betatrophin |
Other Names | Chromosome 19 Open Reading Frame 80, lipasin, Angiopoietin-Like Protein 8, ANGPTL8, PRO1185, PVPA599, RIFL, TD26 and Angpt18 |
Gene, Accession # | Gene ID: 55908 |
Catalog # | 661402 |
Price | |
Order / More Info | Betatrophin Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
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