| 产品详情 |
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| Antigenic Specificity | beta-Dystroglycan |
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| Clone | 7D11 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-β-Dystroglycan. Dystroglycan is a central component of dystrophin-glycoprotein complex that is encoded by the DAG1 gene. Dystroglycan links the cytoskeletal structure to the extracellular matrix. Dystroglycan is proteolytically cleaved to 2 functional peptides, α- and β-dystroglycan. β-dystroglycan is a transmembrane protein, which acts as a cell adhesion receptor in human tissues. The interactions between β-dystroglycan and dystrophin and Utrophin scaffolds axin to the cytoskeleton. β-dystroglycan also has been reported to play a role in cell adhesion-mediated signaling and is implicated in cell polarity. |
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| Immunogen | KLH-conjugated peptide corresponding to the last 15 amino acids (KNMTPYRSPPPYVPP) of L-Dystroglycan. |
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| Other Names | Beta-dystroglycan, Beta-DG |
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| Gene, Accession # | Gene ID: 1605 |
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| Catalog # | 850201 |
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| Price | |
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| Order / More Info | beta-Dystroglycan Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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