产品详情 |
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Antigenic Specificity | beta-Dystroglycan |
Clone | 4F7 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | peroxidase (HRP) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HRP anti-β-Dystroglycan. Dystroglycan is a central component of dystrophin-glycoprotein complex that is encoded by the DAG1 gene. Dystroglycan links the cytoskeletal structure to the extracellular matrix. Dystroglycan is proteolytically cleaved to 2 functional peptides, α- and β-dystroglycan. β-dystroglycan is a transmembrane protein, which acts as a cell adhesion receptor in human tissues. The interactions between β-dystroglycan and dystrophin and Utrophin scaffolds axin to the cytoskeleton. β-dystroglycan has also been reported to play a role in cell adhesion-mediated signaling and is implicated in cell polarity. |
Immunogen | KLH-conjugated peptide corresponding to the last 15 amino acids (KNMTPYRSPPPYVPP) of L-Dystroglycan. |
Other Names | Beta-dystroglycan, Beta-DG, DAG1 |
Gene, Accession # | Gene ID: 1605 |
Catalog # | 849404 |
Price | |
Order / More Info | beta-Dystroglycan Antibody from BIOLEGEND |
Product Specific References | n/a |
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