产品详情 |
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Antigenic Specificity | CD161 |
Clone | HP-3G10 |
Host Species | Mouse |
Reactive Species | human, African green, baboon, cynomolgus, rhesus |
Isotype | IgG1, κ |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-human CD161. CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
Immunogen | Human NK cells |
Other Names | NKR-P1A |
Gene, Accession # | Gene ID: 3820 |
Catalog # | 339936 |
Price | |
Order / More Info | CD161 Antibody from BIOLEGEND |
Product Specific References | n/a |
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