| 产品详情 |
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| Antigenic Specificity | CD172a |
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| Clone | P84 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-mouse CD172a (SIRPα). CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D. |
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| Immunogen | Mouse brain membrane protein |
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| Other Names | SHPS-1, BIT, P84, PTPNS1, CD172 antigen-like family member A |
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| Gene, Accession # | Gene ID: 19261 |
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| Catalog # | 144008 |
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| Price | |
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| Order / More Info | CD172a Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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