| 产品详情 |
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| Antigenic Specificity | Ki-67 |
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| Clone | Ki-67 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: bovine |
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| Isotype | IgG1, κ |
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| Format | Brilliant Violet 605™ conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 605™ anti-human Ki-67. Antigen Ki-67 is a nuclear protein expressed as two isoforms with molecular weights of 395 and 345 kD. Both isoforms contain one forkhead-associated domain and 16 concatenated Ki-67 repeats, each containing the epitope recognized by the mAb Ki-67. The antigen Ki-67 interacts with Hklp2, hNIFK, and chromobox protein homolog 1, 3, and 5. Ki-67 is required for cell proliferation and its expression is restricted to the phases G1, S, G2, and M of the cell cycle. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. Ki-67 has also been used to study myocyte proliferation after myocardial infarction as well as lymphocyte proliferation during infection, and has been used in neurons of patients with different neuropathologies. |
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| Immunogen | Nuclei of the Hodgkin lymphoma cell line L428 |
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| Other Names | Antigen Ki-67 |
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| Gene, Accession # | Gene ID: 4288 |
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| Catalog # | 350521 |
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| Price | |
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| Order / More Info | Ki-67 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 23479624 |
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