产品详情 |
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Antigenic Specificity | EGFR |
Clone | AY13 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-human EGFR. Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the protein kinase superfamily that regulates cell growth and differentiation. EGFR binds EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30, and vaccinia virus growth factor, all members of the EGF family. Ligand binding induces EGFR dimerization and autophosphorylation, initiating the MAPK, Akt, and JNK signaling pathways. EGFR is expressed by epithelial and endothelial cells and is frequently expressed by epithelial carcinomas. |
Immunogen | Non-small cell lung cancer (NSCLC) cell line NCI-H322 |
Other Names | Epidermal growth factor receptor, proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1 |
Gene, Accession # | Gene ID: 1956 |
Catalog # | 352918 |
Price | |
Order / More Info | EGFR Antibody from BIOLEGEND |
Product Specific References | n/a |
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