| 产品详情 |
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| Antigenic Specificity | CD304 |
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| Clone | 3E12 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-mouse CD304 (Neuropilin-1). CD304, also known as neuropilin-1, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain. It is expressed by natural regulatory T cells (nTreg), a subset of invariant natural killer T cells (iNKT), endothelial cells, and neurons. Neuropilin-1 stabilizes the interaction between Tregs and dendritic cells, contributes to the recruitment of tumor-infiltrating Tregs in response to tumor-derived VEGF, and influences the process of angiogenesis and axon guidance. The ligands of CD304 are VEGF165 and semaphorin-3A. |
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| Immunogen | Extracellular region of mouse CD304 |
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| Other Names | NRP, NRP1, VEGFR165 receptor, NPR-1, VEGF165R |
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| Gene, Accession # | Gene ID: 18186 |
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| Catalog # | 145203 |
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| Price | |
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| Order / More Info | CD304 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 24516385,25108241,25238105 |
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