产品详情 |
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Antigenic Specificity | CD304 |
Clone | 3E12 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | biotin conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biotin anti-mouse CD304 (Neuropilin-1). CD304, also known as neuropilin-1, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain. It is expressed by natural regulatory T cells (nTreg), a subset of invariant natural killer T cells (iNKT), endothelial cells, and neurons. Neuropilin-1 stabilizes the interaction between Tregs and dendritic cells, contributes to the recruitment of tumor-infiltrating Tregs in response to tumor-derived VEGF, and influences the process of angiogenesis and axon guidance. The ligands of CD304 are VEGF165 and semaphorin-3A. |
Immunogen | Extracellular region of mouse CD304 |
Other Names | NRP, NRP1, VEGFR165 receptor, NPR-1, VEGF165R |
Gene, Accession # | Gene ID: 18186 |
Catalog # | 145213 |
Price | |
Order / More Info | CD304 Antibody from BIOLEGEND |
Product Specific References | n/a |
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