产品详情 |
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Antigenic Specificity | NOD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:100, Immunofluorescence: 1:50-1:100, Immunohistochemistry: Assay-Dependent, Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NOD2 Polyclonal Antibody. NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease. |
Immunogen | n/a |
Other Names | NOD-2, NOD 2, CARD15, Caspase recruitment domain protein 15, IBD1, Inflammatory Bowel disease protein 1 |
Gene, Accession # | Entrez: 64127; Uniprot: Q9HC29 |
Catalog # | PA1-16859 |
Price | |
Order / More Info | NOD2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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