产品详情 |
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Antigenic Specificity | NOD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NOD1 Polyclonal Antibody. NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detectio |
Immunogen | n/a |
Other Names | Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, NOD1, CARD4 |
Gene, Accession # | Entrez: 10392, 107607, 500133; Uniprot: Q8BHB0, Q9Y239 |
Catalog # | PA5-79747 |
Price | |
Order / More Info | NOD1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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