产品详情 |
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Antigenic Specificity | ERK1/ERK2 |
Clone | 3F8B3 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:300, Immunofluorescence: 1:100-1:300, Immunohistochemistry: 1:200 - 1:1000, Western Blot: 1:1000 |
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Description | ERK1/ERK2 Monoclonal Antibody (3F8B3). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases , act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Immunogen | n/a |
Other Names | ERK; p38; p40; p41; ERK2; ERT1; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; MAPK1 |
Gene, Accession # | Entrez: 116590, 26413, 26417, 50689, 5594, 5595; Uniprot: P21708, P27361, P28482, P63085, P63086, Q63844 |
Catalog # | MA5-15605 |
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Order / More Info | ERK1/ERK2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 28690832 |
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