| 产品详情 |
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| Antigenic Specificity | DAB2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DAB2 Antibody is a Rabbit Polyclonal antibody against DAB2. This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | Recombinant protein of human DAB2. |
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| Other Names | DAB2; Disabled homolog 2; DOC-2; DOC2; Differentially-expressed protein 2; Mitogen-responsive phosphoprotein; mitogen-responsive phosphoprotein (Drosophila); FLJ26626 |
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| Gene, Accession # | DAB2, Gene ID: 1601, SwissProt: P98082 |
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| Catalog # | abx002772 |
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| Price | |
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| Order / More Info | DAB2 Antibody from ABBEXA |
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| Product Specific References | n/a |
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